Mr. Kwame Darkwah | Public Health | Young Scientist Award

Graduate Student | University of Cape Coast | Ghana

Darkwah Kwame Osei is an accomplished researcher with a deep focus on neurodegenerative diseases, neuroimmune interactions, and drug discovery, particularly within the context of the gut-brain axis. Currently, he is pursuing an MSc in Molecular Biology at Jeonbuk National University, South Korea, where his research explores the roles of nitric oxide synthase in Drosophila melanogaster. Osei has a robust academic background, having completed his BSc in Medical Laboratory Science from the University of Cape Coast, Ghana. His work has garnered attention through various publications and presentations in notable journals and academic conferences.

Profile

Orcid

Education
Osei’s educational journey includes a Master’s degree in Molecular Biology from Jeonbuk National University, South Korea (2024), where his thesis focuses on understanding the functional roles of nitric oxide synthase in Drosophila melanogaster. He also holds a Bachelor’s degree in Medical Laboratory Science from the University of Cape Coast, Ghana (2015). His undergraduate research project investigated the use of the RIFLE criteria in diagnosing acute kidney injury among ICU patients, guided by Dr. Richard K.D. Ephraim.

Experience
With extensive research and teaching experience, Osei has contributed significantly to academic life. As a Graduate Research Volunteer at Jeonbuk National University, he helped design plasmids and taught molecular biology techniques such as PCR primer design and gel electrophoresis to undergraduate students. Osei also served as an Undergraduate Research Assistant at the University of Cape Coast, where he supervised student research and assisted in teaching various medical laboratory science courses. His professional experience extends to a role as a Medical Laboratory Scientist at Baiden-Ghartey Hospital, where he led the laboratory department and performed critical diagnostic testing.

Research Interests
Osei’s research interests lie in the intersection of neurodegenerative diseases and neuromodulation, particularly how the gut-brain axis and neuroimmune interactions influence disease processes. His work aims to uncover mechanisms in the brain and immune system that could potentially lead to the development of therapeutic strategies for neurodegenerative diseases. Additionally, he is deeply involved in drug discovery and development, seeking to explore new avenues for treating such complex conditions.

Awards
Osei has earned several prestigious awards, including the Global Korea Scholarship Program (GKSP) for his graduate studies in South Korea (2021-2024). He was also recognized as the Best Graduating Student (2nd rank) in the Medical Laboratory Science Department at the University of Cape Coast, Ghana, a testament to his academic excellence and dedication.

Publications
Osei has contributed to several impactful publications in renowned scientific journals, focusing on health diagnostics and disease mechanisms. His notable publications include:

1. Gyamfi, N. K. A., Osei, G. N., Brenyah, R. C., Agyemang, L. D., Ampomah, P., Darkwah, K. O., … & Ephraim, R. K. (2024). Assessing Concordance of Results: A Comparative Study of the Manual and Automated Urinalysis Methods. BioMed Research International, 2024(1), 6963423.
2. Ephraim, R. K., Ativi, E., Ashie, S. A., Abaka-Yawson, A., & Darkwah, K. O. (2023). Assessment of estimated low-density lipoprotein-cholesterol (LDL-c) equations: a systematic review and meta-analysis. Bulletin of the National Research Centre, 47(1), 71.
3. Ephraim, R. K., Baah, S. K., Sakyi, S. A., Darkwah, K. O., & Abaka-Yawson, A. (2021). Hyperglycaemia in newly diagnosed pulmonary tuberculosis patients: a cross-sectional study of the Agona District Hospital. Annals of Medical Laboratory Science, 1(2), 50-58.
4. Bedu-Addo, K., Ephraim, R. K., Tanoe-Blay, C., Ahenkorah-Fondjo, L., Darkwah, K. O., Ephraim, M., … & Abaka-Yawson, A. (2020). Prevalence and associated factors of fetal macrosomia in a rural community in Ghana. Cogent Medicine, 7(1), 1746602.
5. Anthony, R., Brenyah, R. C., Darkwah, K. O., Egbule, B. C., Ninnoni, J. P., Okantey, C., & Ephraim, R. K. (2019). Hepatitis B Infection in People Living with HIV/AIDS; A Retrospective Study of the Effia Nkwanta Regional Hospital. Journal of Advances in Medicine and Medical Research, 29(8): 1-9.
6. Ephraim, R., Brenyah, R., Osei, B., Anto, E., Basing, A., & Darkwah, K. (2017). Demographic, clinical, and therapeutic characteristics of children aged 0–15 years with nephrotic syndrome: a retrospective study of the Komfo Anokye Teaching Hospital, Kumasi, Ghana. Asian Journal of Medicine and Health, 5(2), 1-9.
7. Adu, P., Dogfobaare, I., Kuuzie, P., Darkwah, K., Twum, B., & Ephraim, R. (2017). No association between Helicobacter pylori infection and type 2 diabetes mellitus; a case-control study in the North-Western part of Ghana. Asian Journal of Medicine and Health, 2(4), 1-7.

Conclusion
Darkwah Kwame Osei’s contributions to the fields of molecular biology, neurodegenerative diseases, and medical laboratory science have made a significant impact on both academic and practical applications. His leadership skills, extensive research, and teaching experience exemplify his dedication to advancing scientific knowledge. As he continues his studies and professional journey, Osei is well-poised to make further strides in understanding complex health issues, especially in the areas of neurology and immunology. With a firm commitment to both education and scientific research, he remains an influential figure in his field.