Dr. Megha K B, an Indian national born on August 9, 1986, resides in Kozhikode, Kerala. She holds a diverse educational background, culminating in a doctoral fellowship specializing in biotechnology, focusing on the therapeutic potential of Thespesia populnea in cancer treatment. She is currently engaged in advanced research in material science and toxicology at Sree Chitra Tirunal Institute for Medical Science and Technology (SCTIMST), Kerala, India.
Publication Profile:
Orcid
Scopus
Education and Experience
Dr. Megha completed her Doctoral Fellowship (2012-2018) at the University of Calicut, Kerala, India, where she investigated the therapeutic potential of Thespesia populnea. Her research was supervised by Dr. K K Elyas in the Department of Biotechnology. She earned her M.Phil in Biomedical Technology from Sree Chitra Tirunal Institute for Medical Science and Technology (SCTIMST), Trivandrum, Kerala, India, in 2010 with a score of 81.94%. She also holds an M.Sc in Biotechnology from Bharathiar University, Coimbatore, Tamil Nadu, India (2009, 80%), and a B.Sc in Microbiology from Kannur University, Kerala, India (2007, 80%).
Professional Experience
- SERB National Post Doctoral Fellow (NPDF) at SCTIMST, Kerala (April 2022 – April 2024), focusing on bone tissue regeneration using novel scaffolds.
- Research Associate at SCTIMST, Kerala (Jan 2020 – April 2022), studying the toxicity of drugs and poloxamers.
- Doctoral Fellow at the University of Calicut, Kerala (Nov 2012 – Dec 2019), researching the antiproliferative activity of Thespesia populnea against cancer cell lines.
- Project Assistant at SCTIMST, Kerala (Oct 2010 – April 2011), validating in vitro pyrogen testing.
- M.Phil Scholar at SCTIMST, Kerala (Aug 2009 – July 2010), evaluating haematological parameters and cytokine release.
- M.Sc Project at Regional Cancer Centre, Kerala (Dec 2008 – March 2009), studying STAT-3 and Cyclin D1 in breast carcinoma.
Professional Development
Dr. Megha has received numerous awards, including the Travel Award at the 7th International Conference on Translational Research (2023) and the Chief Minister’s Nava Kerala Post-Doctoral Fellowship (2022). She has been honored with a Certificate of Appreciation for excellence in research at the 3rd National Biomedical Research Competition (2021) and held various fellowships, including the SERB-NPDF and Southern Tier Cancer Centre USA travel award (2010).
Research Focus
Dr. Megha’s research primarily revolves around the therapeutic potential of medicinal plants, antiproliferative activity against cancer cell lines, bone tissue regeneration, and the toxicity of various compounds. Her work includes the synthesis and characterization of novel scaffolds, in vitro biological assays, and evaluation of bone regeneration models. She is dedicated to advancing biomedical science through innovative research and interdisciplinary collaboration.
Publications
- 3D printed arrowroot starch-gellan scaffolds for wound healing applications (2024) – International Journal of Biological Macromolecules, 8.2 IF
- Development of multifunctional collagen scaffold impregnated with peptide LL-37 for vascularised bone tissue regeneration (2024) – International Journal of Pharmaceutics, 5.8 IF
- Significance of Melatonin in the Regulation of Circadian Rhythms and Disease Management (2023) – Molecular Neurobiology, 5.59 IF
- Comprehensive Risk Assessment of Infection Induced by SARS-CoV-2 (2023) – Molecular Neurobiology, 5.59 IF
- Cellular consequences triggered by ketamine on exposure to human glioblastoma epithelial (LN-229) cells (2023) – Journal of Biochemical and Molecular Toxicology, 3.6 IF
- Blood-brain barrier-on-a-chip to model neurological diseases (2023) – Journal of Drug Delivery Science and Technology, 5.062 IF
- Elucidating the synergistic capability of phytoconstituents in Thespesia populnea towards enhanced cytotoxicity against K562 leukemic cells (2022) – IOSR Journal of Pharmacy and Biological Sciences, —
- Cytocompatibility of pluronic F-127 on adenocarcinomic human alveolar basal epithelial cells (2022) – Environmental Science and Pollution Research, 5.8 IF
- Assessment of Inflammatory Response on Pyrogenic Induction by In vitro and In vivo Methods (2021) – Biointerface Research in Applied Chemistry, 2.23 IF
- Vaccines and vaccination as part of human life. In view of Covid-19 (2021) – Biotechnology Journal, 4.7 IF