Prof. Zhichao Miao | Bioinformatics | Best Researcher Award

Prof. Zhichao Miao | Bioinformatics | Principal Investigator at Guangzhou Medical University | China

Prof. Zhichao Miao is a distinguished Principal Investigator and computational biologist whose expertise bridges bioinformatics, single-cell genomics, and RNA structural biology. He earned his Ph.D. in Bioinformatics from the Institute of Biophysics, Chinese Academy of Sciences, and his Bachelor’s degree in Bioengineering from the Harbin Institute of Technology, laying a strong foundation in computational and molecular biology. Professionally, Prof. Miao has held esteemed research appointments at world-class institutions such as the European Bioinformatics Institute (EMBL-EBI) and the Wellcome Trust Sanger Institute in the United Kingdom, where he contributed to pioneering genomic data integration projects. Currently serving as Principal Investigator at Guangzhou National Laboratory and Adjunct Professor at Guangzhou Medical University, he leads innovative programs in AI-driven multi-omics, digital twin cell technology, and RNA informatics. His research interests center on computational modeling of gene expression, cross-species cell type mapping, and algorithmic optimization for biological data analysis. With a remarkable publication record of over 68 SCI-indexed papers, an H-index of 32, and more than 8,000 citations, his work has appeared in high-impact journals including Nature Medicine, Nature Methods, Nature Communications, and Nucleic Acids Research. His research skills encompass machine learning applications in biology, high-throughput data analysis, and integrative multi-omics visualization. Prof. Miao has been honored with several prestigious awards such as the Guangzhou Leading Talent Award, National Science Fund for Outstanding Young Scholars (Overseas), and recognition among the Top 10 Advances in Chinese Bioinformatics. Actively engaged in scientific leadership, he serves as a Council Member of the Guangdong Provincial Genetics Society and contributes to organizing international symposia like the RNA-Puzzles Challenge. In conclusion, Prof. Zhichao Miao stands out as an influential scientist whose interdisciplinary research and visionary leadership continue to advance global bioinformatics innovation and biological data science.

Profile: Google Scholar

Featured Publications

1. Sungnak, W., Huang, N., Bécavin, C., Berg, M., Queen, R., Litvinukova, M., … & Miao, Z. (2020). SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes. Nature Medicine, 26(5), 681–687. Citations: 3006

2. Polański, K., Young, M. D., Miao, Z., Meyer, K. B., Teichmann, S. A., & Park, J. E. (2020). BBKNN: fast batch alignment of single-cell transcriptomes. Bioinformatics, 36(3), 964–965. Citations: 843

3. Popescu, D. M., Botting, R. A., Stephenson, E., Green, K., Webb, S., Jardine, L., … & Miao, Z. (2019). Decoding human fetal liver haematopoiesis. Nature, 574(7778), 365–371. Citations: 589

4. Büttner, M., Miao, Z., Wolf, F. A., Teichmann, S. A., & Theis, F. J. (2019). A test metric for assessing single-cell RNA-seq batch correction. Nature Methods, 16(1), 43–49. Citations: 485

5. Muus, C., Luecken, M. D., Eraslan, G., Sikkema, L., Waghray, A., Heimberg, G., … & Miao, Z. (2021). Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics. Nature Medicine, 27(3), 546–559. Citations: 381

6. Miao, Z., Adamiak, R. W., Antczak, M., Batey, R. T., Becka, A. J., Biesiada, M., … & Westhof, E. (2017). RNA-Puzzles Round III: 3D RNA structure prediction of five riboswitches and one ribozyme. RNA, 23(5), 655–672. Citations: 216

7. Miao, Z., Westhof, E. (2017). RNA structure: advances and assessment of 3D structure prediction. Annual Review of Biophysics, 46(1), 483–503. Citations: 206