Ge Zhang | Cardiology | Research Excellence Award

Prof. Ge Zhang | Cardiology | Research Excellence Award

Prof. Ge Zhang | Cardiology | Chair Professor at Hong Kong Baptist University | Hong Kong

Cardiology defines the central theme of Prof. Ge Zhang’s distinguished academic and research career, reflecting his multidisciplinary expertise in biomedicine, metabolic and endocrine disorders, oncology, and translational medicine. Prof. Ge Zhang obtained his foundational education in Chinese Medicine and Orthopaedics at Shanghai University of Chinese Medicine, followed by advanced research training at The Chinese University of Hong Kong, laying the groundwork for a career that integrates clinical insights with molecular and translational research. Prof. Ge Zhang began his professional journey as a resident and physician-in-charge in orthopaedics and traumatology, progressing to postdoctoral and research assistant professorships, before ascending to professorial and directorial roles in the School of Chinese Medicine at Hong Kong Baptist University (HKBU), where he currently serves as Chair Professor and Associate Dean. His professional experience spans clinical practice, biomedical research, technology development, and academic leadership, with key appointments including Director of the Institute for Advancing Translational Medicine in Bone & Joint Diseases and leadership of the Technology Development Division at HKBU. Prof. Ge Zhang’s research interests converge on cardiovascular diseases, metabolic bone and endocrine disorders, oncology, and drug discovery, emphasizing aptamer-based therapeutics and translational medicine strategies. His lab focuses on understanding the molecular mechanisms underlying cardiovascular regulation, tumor-targeted therapy, muscle regeneration, and neuroinflammation, employing cutting-edge techniques such as peptide and stapled aptamer design, extracellular vesicle delivery, real-time RT-PCR, and molecular modeling for therapeutic development. Prof. Ge Zhang’s research skills encompass molecular biology, medicinal chemistry, pharmacology, translational modeling, assay development, and the integration of clinical insights into laboratory discovery, enabling the design and evaluation of novel therapeutics with high specificity and efficacy. Throughout his career, Prof. Ge Zhang has received numerous honors recognizing both scientific innovation and academic leadership, including awards for translational research excellence, technological invention in therapeutic development, and recognition in international peer-reviewed journals. In conclusion, Prof. Ge Zhang exemplifies a visionary scientist whose integration of cardiology, molecular medicine, and translational strategies has advanced both clinical practice and therapeutic discovery, establishing him as a leading figure in cardiovascular research, aptamer-based drug development, and interdisciplinary biomedicine, while mentoring the next generation of scholars and bridging the gap between laboratory science and patient-centered applications.

Profile: ORCID

Featured Publications 

Zhang, G. (2025). Role of Sclerostin in Cardiovascular System. International Journal of Molecular Sciences. Cited by 4
Zhang, G. (2024). Peptide Aptamer–Paclitaxel Conjugates for Tumor Targeted Therapy. Pharmaceutics. Cited by 8
Zhang, G. (2024). Long Noncoding RNA lncRNA-3 Recruits PRC2 for MyoD1 Silencing to Suppress Muscle Regeneration During Aging. International Journal of Molecular Sciences. Cited by 5
Zhang, G. (2024). Developing Stapled Aptamers with a Constrained Conformation for Osteogenesis Imperfect Therapeutics. Journal of Medicinal Chemistry. Cited by 6
Zhang, G. (2024). Inflammatory Processes: Key Mediators of Oncogenesis and Progression in Pancreatic Ductal Adenocarcinoma (PDAC). International Journal of Molecular Sciences. Cited by 8
Zhang, G. (2024). Peptide-Conjugated Vascular Endothelial Extracellular Vesicles Encapsulating Vinorelbine for Lung Cancer Targeted Therapeutics. Nanomaterials. Cited by 5
Zhang, G. (2024). Connective Tissue Growth Factor: Regulation, Diseases, and Drug Discovery. International Journal of Molecular Sciences. Cited by 13
Zhang, G. (2023). Exploring the Potential of Aptamers in Targeting Neuroinflammation and Neurodegenerative Disorders: Opportunities and Challenges. International Journal of Molecular Sciences. Cited by 19
Zhang, G. (2023). Development of a Real-Time TaqMan RT-PCR Assay for the Detection of NADC34-like Porcine Reproductive and Respiratory Syndrome Virus. Veterinary Sciences. Cited by 7

 

Rosalinda Madonna | Cardiovascular diseases | Women Researcher Award

Prof. Rosalinda Madonna | Cardiovascular diseases | Women Researcher Award

Associate Professor, MD PhD | University of Pisa, Azienda Ospedaliera Universitaria Pisana |  Italy

Based on the provided information about Rosalinda Madonna, here’s an assessment of her suitability for the Research for Women Researcher Award, focusing on her strengths, areas for improvement, and a conclusion:

Strengths for the Award

  1. Extensive Research Experience: Rosalinda Madonna’s extensive research background, spanning several high-impact projects, demonstrates her depth of knowledge and leadership in cardiology and molecular medicine. Her involvement as a principal investigator in numerous grants, including NIH, Department of Defense, and PRIN, highlights her ability to secure funding and lead significant research initiatives.
  2. Diverse and Impactful Research Topics: Her work covers a broad range of topics, from stem cells in diabetes to the molecular mechanisms of cardiovascular diseases and pulmonary arterial hypertension. This diversity showcases her versatility and commitment to advancing medical science.
  3. International Recognition and Collaboration: Madonna’s research has earned her international recognition and collaborative opportunities, including roles at prominent institutions in the U.S. and Italy. Her citation index (H-index from Scopus: 46; Google Scholar: 54) reflects the high impact and relevance of her work.
  4. Publication Record: With numerous publications in notable books and peer-reviewed journals, her contributions to the field are well-documented and influential. Her publications address critical issues in cardiovascular health, stem cell research, and gene expression.
  5. Leadership in Research Initiatives: As a Principal Investigator in multiple ongoing and completed projects, Madonna has demonstrated leadership in shaping research agendas and fostering innovation.

Areas for Improvement

  1. Broader Impact Metrics: While her citation indices are strong, more emphasis on the real-world impact of her research could strengthen her profile. Including specific examples of how her findings have influenced clinical practice or policy could enhance her application.
  2. Interdisciplinary Integration: Although Madonna has made significant strides in cardiology and molecular medicine, exploring interdisciplinary collaborations beyond these fields might open new avenues for impactful research.
  3. Public Engagement and Outreach: Increasing engagement with the public and broader scientific community through public talks, media, or outreach programs could enhance the visibility of her work and its societal impact.
  4. Mentorship and Training: Providing more information on her role in mentoring young researchers and her contributions to educational programs would add depth to her profile, highlighting her influence on the next generation of scientists.

Conclusion

Rosalinda Madonna is a highly qualified candidate for the Research for Women Researcher Award. Her extensive research experience, significant contributions to cardiology and molecular medicine, international recognition, and robust publication record underscore her suitability for this award. Addressing areas such as broader impact metrics, interdisciplinary integration, public engagement, and mentorship could further enhance her profile. Overall, her impressive achievements and ongoing research make her a standout candidate for recognition in this prestigious award.

Short Bio:

Rosalinda Madonna is an Associate Professor of Cardiology at the University of Pisa. With a robust career spanning from research fellowships in the U.S. to leading a Molecular Cardiology Laboratory in Italy, she is renowned for her work in cardiovascular diseases and molecular cardiology.

Profile

ORCID

Education:

Rosalinda Madonna has a comprehensive educational background in cardiology and molecular medicine, bolstered by her research fellowships at esteemed institutions such as the University of Texas Medical School and University of Louisville.

Experience:

Madonna’s career includes pivotal roles such as Research Scientist at the Texas Heart Institute and Adjunct Assistant Professor in Cardiology at the University of Texas Medical School. She currently leads the Molecular Cardiology Laboratory and outpatient clinic at the University of Pisa.

Research Interests:

Her research focuses on molecular mechanisms in cardiovascular diseases, stem cells, and pulmonary arterial hypertension. She investigates novel therapeutic targets and pathophysiological mechanisms in these areas.

Awards:

Rosalinda Madonna has received multiple prestigious awards and grants, including from the NIH, Department of Defense, and MIUR, reflecting her significant contributions and impact in her field.

Publications:

De Caterina R, Madonna R, Hassan J, Procopio AD (2001). “Nutrients and gene expression.” World Review of Nutrition and Dietetics, vol. 89, pp. 23-52.

Madonna R, Torge G, Di Napoli P, De Caterina R (2002). “La Sindrome da basse HDL.” I Quaderni del CNR, pp. 92-101.

Zampolli A, Madonna R, De Caterina R (2002). “Altri fattori di rischio.” I Quaderni del CNR, pp. 162-181.

De Caterina R, Madonna R (2005). “Role of Nutrients and physical activity in gene expression.” World Review of Nutrition and Dietetics, vol. 94, pp. 107-119.

Geng YJ, Madonna R (2005). “Stem Cells in Atherosclerosis.” Current Topics in Atherosclerosis Research, pp. 147-164.

Madonna R, De Caterina R (2007). “Homocysteine and endothelial dysfunction.” Cardiology Research and Clinical Developments, pp. 129-139.

Geng YJ, Madonna R (2007). “Stem Cells in Atheriosclerosis and Atherosclerosis-related vascular disorders.” Endothelial Dysfunctions and Vascular Disease.

Madonna R, De Caterina R (2011). “Cell-Based Gene Therapies and Stem Cells for Regeneration of Ischemic Tissues.” Gene Therapy Applications, pp. 17-34.

Madonna R, De Caterina R (2012). “Tissue-specific progenitor cells.” Progenitor and Stem Cell Technologies and Therapies, pp. 237-262.