Garagan Ivan | Organic chemistry | Best Researcher Award

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Mr. Garagan Ivan | Organic chemistry | Best Researcher Award

Mr. Garagan Ivan | Organic chemistry-PhD at Irkutsk State University, Russia

Garagan Ivan Alexandrovich is a dedicated researcher specializing in organic chemistry, particularly in the development of oxidative sulfonamidation reactions and their application in drug design. With a deep understanding of chemical reactivity and structure, he has significantly contributed to the synthesis of biologically active compounds, focusing on the modification of unsaturated substrates and terpenes. As a member of the Federal State Research Center “Irkutsk Institute of Chemistry,” Garagan has co-authored multiple publications in leading journals and has been involved in various scientific projects funded by the Russian Science Foundation. His research has not only advanced theoretical chemistry but also has potential implications for the development of new pharmaceutical agents.

Profile:

Orcid

Education:

Garagan Ivan Alexandrovich’s educational journey began at Irkutsk State University, where he obtained his Bachelor’s degree in 2017 and Master’s degree in 2019. His academic background provided a solid foundation in organic chemistry, which he later applied in his innovative research. His dedication culminated in his successful defense of his PhD thesis in 2023, titled “Oxidative Sulfonamidation of Unsaturated Substrates – The Way to New Amidines and Heterocycles.” This work highlighted his expertise in chemical reactions that could lead to the development of novel drugs, demonstrating his potential as a leader in his field.

Experience:

Since 2019, Garagan has been an active member of the laboratory of organoelement compounds at the Irkutsk Institute of Chemistry, where he has developed expertise in organometallic chemistry and oxidation reactions. His involvement in key research projects, including those funded by the Russian Science Foundation, demonstrates his active contribution to both theoretical and practical chemistry. Over the years, Garagan has been part of a team that developed triflamidation reactions and studied the sulfonamide modification of terpenes, paving the way for new chemical methodologies with significant biological relevance. His professional experience extends to presenting his findings at conferences, where his research continues to gain recognition among peers.

Research Interests:

Garagan’s primary research interest lies in the development of oxidative sulfonamidation reactions involving unsaturated substrates, with a focus on their use in drug development. His work is centered on synthesizing biologically active compounds, including heterocycles and amidines, through selective chemical processes. This research not only contributes to the academic understanding of organic chemistry but also holds promise for the creation of new therapeutic agents. Additionally, his studies on the modification of terpenes using sulfonamide groups explore how natural compounds can be tailored to serve as the basis for novel pharmaceutical drugs. His work contributes to advancing both the basic and applied sciences within organic chemistry.

Awards:

Garagan Ivan Alexandrovich has been recognized for his outstanding contributions to organic chemistry. His active participation in high-profile scientific conferences, such as the “Actual Problems of Organic Chemistry” conference in 2024, showcases his commitment to sharing his research with the broader scientific community. Furthermore, his involvement in two Russian Science Foundation grants demonstrates the significance of his work in advancing chemical research. These grants, focused on amidation of monoterpenes and the development of new heterocyclic compounds, highlight Garagan’s integral role in groundbreaking scientific endeavors.

Publications:

Garagan has authored and co-authored several key publications in high-impact journals, contributing significantly to the field of organic chemistry. Some of his notable works include:

  1. “Halosulfonamidation of Camphene: Chemo and Stereoselectivity, Rearrangement, Solvent Interception, Heterocyclization” (2024) in New Journal of Chemistry
    DOI: 10.1039/D4NJ02582B
    This article discusses the chemo and stereoselectivity of halosulfonamidation reactions in camphene, exploring the mechanisms and solvent effects.
  2. “N-(4-Iodo-1,3-diphenylbutyl)acetamide: Nature and Strength of Hydrogen Bonds in Crystal and Solutions” (2023) in Russian Journal of General Chemistry
    DOI: 10.1134/S1070363223100225
    This publication focuses on the analysis of hydrogen bonds in crystal structures, offering insights into molecular interactions.
  3. “Synthesis and Structure of N-(1-(Bromomethyl)-7,7-dimethylbicyclo[2.2.1]heptan-2-yl)benzenesulfonamide” (2023) in MolBank
    DOI: 10.3390/M1645
    The article presents the synthesis and characterization of a novel sulfonamide compound with potential applications in drug design.
  4. “Regioselective Oxidative Halotriflamidation of Dienes and Trienes as a Route to New Amidines and Heterocycles” (2022) in ChemistrySelect
    DOI: 10.1002/SLCT.202202231
    This paper outlines the selective triflamidation of dienes and trienes, contributing to the development of new heterocyclic compounds.
  5. “Triflamidation of Allyl-Containing Substances: Unusual Dehydrobromination vs. Intramolecular Heterocyclization” (2022) in Molecules
    DOI: 10.3390/MOLECULES27206910
    This article discusses the triflamidation of allyl substances, providing insights into unusual reaction pathways and potential applications in chemical synthesis.
  6. “Oxidative Sulfonamidation of O-containing Vinylsilanes. A New Route to Novel Heterocycles and Amidines” (2021) in Journal of Organometallic Chemistry
    DOI: 10.1016/J.JORGANCHEM.2021.122010
    The study investigates new oxidative sulfonamidation routes for synthesizing heterocycles, showcasing novel methodologies for organic synthesis.
  7. “Solvent-Dependent Oxidative Triflamidation of Alkenes and N(O)-Heterocyclization of the Products” (2021) in Tetrahedron
    DOI: 10.1016/J.TET.2021.132145
    This paper explores the solvent-dependent oxidative triflamidation of alkenes, contributing to the understanding of solvent effects on chemical reactions.

Conclusion:

Garagan Ivan Alexandrovich is a distinguished researcher whose work has advanced the field of organic chemistry, particularly in the synthesis of biologically active compounds and the development of new chemical reactions for drug discovery. His contributions to oxidative sulfonamidation and heterocyclization have the potential to impact various areas, including pharmaceutical development and medicinal chemistry. His active participation in high-impact research projects, collaboration with leading researchers, and significant publications solidify his reputation as a leader in his field. As a promising scientist with a bright future, Garagan’s innovative contributions make him a worthy candidate for the Best Researcher Award, and his continued research is likely to further shape the future of organic chemistry and drug development.

Kowsar Bagherzadeh | Chemistry | Best Researcher Award

Published on by Academic Achievements

Dr. Kowsar Bagherzadeh | Chemistry | Best Researcher Award

Assistant Professor | Iran University of Medical Sciences | Iran

A highly skilled Computational Chemist with over 15 years of experience, the individual specializes in molecular modeling and simulations. With expertise in advanced techniques such as Molecular Dynamics Simulations, Umbrella Sampling, and QM/MM Metadynamics, their work investigates complex chemical and biochemical systems. The focus is on molecular screening, design, and development, aiming to contribute to advancements in diagnostics, therapeutics, and detection technologies.

Profile

Scholar

Education: This professional holds a PhD in Analytical Chemistry from the University of Tehran (2009-2014) and an MS in Analytical Chemistry from the same institution (2006-2008). Additionally, they earned a Health MBA from Sharif University of Technology (2019-2020). Their foundational education includes a BS in Applied Chemistry from the Islamic Azad University of Tehran (2001-2005), as well as a BA in English Literature from the University of Tehran (2001-2005), demonstrating a diverse academic background.

Experience: With a well-established career, they currently serve as a Full-Time Research Assistant Professor and Executive Director at the Eye Research Center, Five Senses Institute, Iran University of Medical Sciences (IUMS), since 2020. In the same year, they became a Part-Time Assistant Professor at the Stem Cell & Regenerative Medicine Research Center, IUMS. Previously, they held leadership roles, including Editor-in-Chief of the Iranian Journal of Pharmacology and Therapeutics (2017-2020), and served in various administrative positions, such as in the Chancellery of International Affairs and Research and Technology at IUMS.

Research Interest: The individual’s research interests focus on computational techniques, including Molecular Dynamics Simulations and Metadynamics, to explore molecular interactions. They specialize in in silico design of biotherapeutics and structural bioinformatics, using advanced modeling to engineer molecules for therapeutics, diagnostics, and detection technologies. This research is vital for the development of novel drug designs, diagnostics, and sensor technologies, particularly in oncology, immunotherapy, and environmental monitoring.

Award: The professional’s accomplishments have been recognized by numerous awards, including being named a “Chosen Young Scientist” by Rassoul-e-Akram Hospital, IUMS (2020). They received the Best Topic Award at the National Students Congress on Pharmaceutical Sciences (2014) and a Best Poster Award at the Discovery Chemistry International Congress in Barcelona (2014). Their recognition also extends to being honored as a Gifted Student at the University of Tehran (2008).

Publication: They have authored several significant publications. Key works include “Computational Engineering of Protein L to Achieve an Optimal Affinity Chromatography Resin for Purification of Antibody Fragments” (Analytical Chemistry, 2021), “Human IL-2Rɑ Subunit Binding Modulation of IL-2 Through a Decline in Electrostatic Interactions” (PloS One, 2022), and “Key Criteria for Engineering Mycotoxin Binding Aptamers via Computational Simulations” (Biotechnology Journal, 2022). Other notable papers include research on electrochemical sensors for tetracycline detection (Food Chemistry, 2023), and the destruction mechanisms of ozone over SARS-CoV-2 (Scientific Reports, 2021). These publications highlight their proficiency in computational chemistry and molecular simulations.

Conclusion: A proven leader in computational chemistry, this individual blends extensive research experience with academic teaching and project management. With advanced skills in molecular simulations and bioinformatics, they play a pivotal role in advancing research in diagnostics, therapeutics, and environmental science. Their work stands out for its depth, particularly in computational modeling and simulations applied to biotherapeutics. By continuing to expand their research and collaborations, they are poised to make significant contributions to future innovations in molecular science and technology.