PhD at Technical University Munich, Germany
Dr. Vini Tiwari is an emerging neuroscientist dedicated to advancing the understanding of neurodegenerative diseases and glial cell biology. Currently associated with the Institute of Neuronal Cell Biology at the Technical University of Munich (TUM-NCB) and the German Center for Neurodegenerative Diseases (DZNE), Dr. Tiwari is making significant contributions to research on remyelination, neuroepigenetics, and neuroimmunology. With a strong academic foundation and a commitment to tackling complex neurological challenges, Dr. Tiwari has earned recognition for excellence in research presentations and contributions to prestigious neuroscience platforms worldwide. Her work reflects a dedication to developing innovative therapeutic approaches for neurological disorders.
Profile
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Education
Dr. Tiwari’s educational journey in neuroscience began with a Bachelor of Science in Botany, with minors in Zoology, Chemistry, and Industrial Microbiology, from Banaras Hindu University, Varanasi, India, where she graduated summa cum laude in 2016. She then pursued a Master of Science in Neuroscience at the National Brain Research Centre (NBRC) in Gurgaon, India, completing her degree in 2018 with top honors. Driven by a passion for unraveling the complexities of the human brain, she commenced her Ph.D. in Neuroscience at the Graduate School of Systemic Neurosciences, Ludwig Maximilian University (GSN-LMU), Munich, in October 2018, completing it in February 2024. Throughout her academic journey, Dr. Tiwari maintained a consistent track record of academic excellence, earning several merit-based awards.
Experience
Dr. Tiwari’s research experience is rooted in the fields of neurodegenerative disease and glial cell biology. Her doctoral research at DZNE focused on mechanisms underlying remyelination, neuroimmunology, and neuroepigenetics, contributing significantly to understanding the role of glial cells in brain repair. Her expertise extends to primary cell culture, molecular biology techniques, microdissection, and advanced bioinformatics analyses using techniques such as ATAC-seq and RNA-seq. Dr. Tiwari has also demonstrated her skills in animal research, including conditional knockout models and stereotactic injections in mice, further underscoring her versatile research capabilities. She has been an invited speaker at various prestigious forums and has actively participated in neuroscience conferences globally, presenting her work on microglia and neuroimmune responses.
Research Interest
Dr. Tiwari’s research interests lie at the intersection of neurodegeneration, glial biology, and neuroinflammation. Her work aims to elucidate the molecular mechanisms driving neurodegenerative disorders and develop strategies to enhance brain repair processes, especially remyelination. She is particularly focused on understanding the role of innate immune responses and epigenetic modifications in neurodegenerative disease progression and recovery. By investigating the cellular and molecular pathways involved in glial cell function, Dr. Tiwari aims to pave the way for innovative therapies that can alleviate or even reverse the effects of neurodegenerative diseases such as multiple sclerosis and Alzheimer’s disease.
Awards
Dr. Tiwari has received numerous accolades throughout her career. These include travel grants from SyNergy (Munich Cluster for Systems Neurology) for international and European travel, reflecting recognition of her work in the neuroscience community. She was also honored with the People’s Choice award for her presentation at the Indo-Swiss Genetic Variant Analysis program. Earlier in her academic career, she secured the prestigious National Master’s Fellowship from India’s Department of Biotechnology for her master’s studies at NBRC. Her consistent academic performance has earned her several other awards, including multiple gold medals during her undergraduate studies at Banaras Hindu University.
Publications
Dr. Tiwari has published several impactful papers, showcasing her contributions to neurodegenerative research. Some of her notable publications include:
Vini Tiwari et al., Innate immune training restores myeloid responses to promote remyelination in the aged central nervous system, Immunity, 2024. DOI: 10.1016/j.immuni.2024.07.001.
Hao Ji, Beatrice Dalla Volta, Vini Tiwari, et al., Designed Macrocyclic Peptide Reduces Amyloid Deposition and Neurological Damage in Murine Alzheimer’s Disease Models, Nature Communications, 2024 (in revision).
Felicitas Selter, Tatiana Hetzel, Vini Tiwari*, et al., From Ethical Presumptions to conducting animal research to publishing results and back again – Towards a more complete account of Animal research Ethics, Animals, 2024. DOI: 10.3390/ani14192896.
Mar Bosch-Queralt, Vini Tiwari et al., A fluorescence microscopy-based protocol for volumetric measurement of lysolecithin lesion-associated de- and remyelination in mouse brain, Star Protocols, 2022. DOI: 10.1016/j.celrep.2021.109898.
Horst Penkert, Alix Bertrand, Vini Tiwari, et al., Proteomic and lipidomic profiling of demyelinating lesions identifies lipid mediators as modulators in inflammation resolution, Cell Reports, 2021. DOI: 10.1016/j.celrep.2021.109898.
K.G. Rolland, H. S. Pandey, V. Tiwari et al., Cytoprotective action of Griffonia simplicifolia (DC.) Baill. against the oxidative stress caused by hydrogen peroxide (H2O2) on neurons and astrocytes, GSC Biological and Pharmaceutical Sciences, 2018. DOI: 10.30574/gscbps.2018.5.
Conclusion
Dr. Vini Tiwari’s impressive track record in research, presentations, and publications makes her a strong candidate for the “Best Researcher Award.” Her dedication to exploring the complex interplay between glial cells and neurodegeneration, coupled with her consistent academic excellence, positions her as an emerging leader in neuroscience. With ongoing projects that hold promise for significant therapeutic advancements, Dr. Tiwari is poised to continue making meaningful contributions to the field of neurodegenerative research.