Prof. Xiang Xu | Sepsis |Director at Amy Medical University | China
Prof. Xiang Xu, Distinguished Professor of Cytotherapeutics at Amy Medical University, grew up in China and earned his doctoral degree from the Third Military Medical University. He conducted postdoctoral research at Pittsburgh University on “HDAC2 promoting eIF4E sumoylation and activating mRNA translation gene specifically.” Prof. Xiang Xu then joined the first department at the State Key Laboratory of Trauma, Burn and Combined Injury in China as a principal investigator, leading stem cell and regenerative medicine research. He founded and became director of the Department of Stem Cell & Regenerative Medicine at Daping Hospital, Amy Medical University, focusing on basic, translational, and clinical research in immunocyte-based and stem cell-based therapies. Prof. Xiang Xu developed a novel therapeutic strategy combining human umbilical cord mesenchymal stem cell transplantation with IFN-gamma to improve rheumatoid arthritis outcomes. He has published over 60 SCI papers in top journals including Mol Cancer, Ann Rheum Dis, J Adv Res, and Adv Materials, earning numerous awards and recognition for his contributions to cytotherapeutics and regenerative medicine.
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Featured Publications
Mesenchymal stem cells combined with IFN-γ treatment versus mesenchymal stem cells monotherapy: safety and efficacy over five years extension follow-up – Stem Cell Research and Therapy, 2025
Neutrophilic granule protein promotes lipopolysaccharide-induced iNOS/NO expression via JAK2/STAT1 signaling pathway and augments bacteria clearance of macrophages – Cellular and Molecular Life Sciences, 2025
Crosstalk between heterogeneous cancer-associated fibroblast subpopulations and the immune system in breast cancer: key players and promising therapeutic targets – Review, 2025
Gene therapy prevents onset of mitochondrial cardiomyopathy in neonatal mice with Ndufs6 deficiency – Cell Death Discovery, 2025
Lactate-mediated lactylation in human health and diseases: Progress and remaining challenges – Review, 2025