Mr. Garagan Ivan | Organic chemistry-PhD at Irkutsk State University, Russia
Garagan Ivan Alexandrovich is a dedicated researcher specializing in organic chemistry, particularly in the development of oxidative sulfonamidation reactions and their application in drug design. With a deep understanding of chemical reactivity and structure, he has significantly contributed to the synthesis of biologically active compounds, focusing on the modification of unsaturated substrates and terpenes. As a member of the Federal State Research Center “Irkutsk Institute of Chemistry,” Garagan has co-authored multiple publications in leading journals and has been involved in various scientific projects funded by the Russian Science Foundation. His research has not only advanced theoretical chemistry but also has potential implications for the development of new pharmaceutical agents.
Profile:
Education:
Garagan Ivan Alexandrovich’s educational journey began at Irkutsk State University, where he obtained his Bachelor’s degree in 2017 and Master’s degree in 2019. His academic background provided a solid foundation in organic chemistry, which he later applied in his innovative research. His dedication culminated in his successful defense of his PhD thesis in 2023, titled “Oxidative Sulfonamidation of Unsaturated Substrates – The Way to New Amidines and Heterocycles.” This work highlighted his expertise in chemical reactions that could lead to the development of novel drugs, demonstrating his potential as a leader in his field.
Experience:
Since 2019, Garagan has been an active member of the laboratory of organoelement compounds at the Irkutsk Institute of Chemistry, where he has developed expertise in organometallic chemistry and oxidation reactions. His involvement in key research projects, including those funded by the Russian Science Foundation, demonstrates his active contribution to both theoretical and practical chemistry. Over the years, Garagan has been part of a team that developed triflamidation reactions and studied the sulfonamide modification of terpenes, paving the way for new chemical methodologies with significant biological relevance. His professional experience extends to presenting his findings at conferences, where his research continues to gain recognition among peers.
Research Interests:
Garagan’s primary research interest lies in the development of oxidative sulfonamidation reactions involving unsaturated substrates, with a focus on their use in drug development. His work is centered on synthesizing biologically active compounds, including heterocycles and amidines, through selective chemical processes. This research not only contributes to the academic understanding of organic chemistry but also holds promise for the creation of new therapeutic agents. Additionally, his studies on the modification of terpenes using sulfonamide groups explore how natural compounds can be tailored to serve as the basis for novel pharmaceutical drugs. His work contributes to advancing both the basic and applied sciences within organic chemistry.
Awards:
Garagan Ivan Alexandrovich has been recognized for his outstanding contributions to organic chemistry. His active participation in high-profile scientific conferences, such as the “Actual Problems of Organic Chemistry” conference in 2024, showcases his commitment to sharing his research with the broader scientific community. Furthermore, his involvement in two Russian Science Foundation grants demonstrates the significance of his work in advancing chemical research. These grants, focused on amidation of monoterpenes and the development of new heterocyclic compounds, highlight Garagan’s integral role in groundbreaking scientific endeavors.
Publications:
Garagan has authored and co-authored several key publications in high-impact journals, contributing significantly to the field of organic chemistry. Some of his notable works include:
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“Halosulfonamidation of Camphene: Chemo and Stereoselectivity, Rearrangement, Solvent Interception, Heterocyclization” (2024) in New Journal of Chemistry
DOI: 10.1039/D4NJ02582B
This article discusses the chemo and stereoselectivity of halosulfonamidation reactions in camphene, exploring the mechanisms and solvent effects.
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“N-(4-Iodo-1,3-diphenylbutyl)acetamide: Nature and Strength of Hydrogen Bonds in Crystal and Solutions” (2023) in Russian Journal of General Chemistry
DOI: 10.1134/S1070363223100225
This publication focuses on the analysis of hydrogen bonds in crystal structures, offering insights into molecular interactions.
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“Synthesis and Structure of N-(1-(Bromomethyl)-7,7-dimethylbicyclo[2.2.1]heptan-2-yl)benzenesulfonamide” (2023) in MolBank
DOI: 10.3390/M1645
The article presents the synthesis and characterization of a novel sulfonamide compound with potential applications in drug design.
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“Regioselective Oxidative Halotriflamidation of Dienes and Trienes as a Route to New Amidines and Heterocycles” (2022) in ChemistrySelect
DOI: 10.1002/SLCT.202202231
This paper outlines the selective triflamidation of dienes and trienes, contributing to the development of new heterocyclic compounds.
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“Triflamidation of Allyl-Containing Substances: Unusual Dehydrobromination vs. Intramolecular Heterocyclization” (2022) in Molecules
DOI: 10.3390/MOLECULES27206910
This article discusses the triflamidation of allyl substances, providing insights into unusual reaction pathways and potential applications in chemical synthesis.
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“Oxidative Sulfonamidation of O-containing Vinylsilanes. A New Route to Novel Heterocycles and Amidines” (2021) in Journal of Organometallic Chemistry
DOI: 10.1016/J.JORGANCHEM.2021.122010
The study investigates new oxidative sulfonamidation routes for synthesizing heterocycles, showcasing novel methodologies for organic synthesis.
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“Solvent-Dependent Oxidative Triflamidation of Alkenes and N(O)-Heterocyclization of the Products” (2021) in Tetrahedron
DOI: 10.1016/J.TET.2021.132145
This paper explores the solvent-dependent oxidative triflamidation of alkenes, contributing to the understanding of solvent effects on chemical reactions.
Conclusion:
Garagan Ivan Alexandrovich is a distinguished researcher whose work has advanced the field of organic chemistry, particularly in the synthesis of biologically active compounds and the development of new chemical reactions for drug discovery. His contributions to oxidative sulfonamidation and heterocyclization have the potential to impact various areas, including pharmaceutical development and medicinal chemistry. His active participation in high-impact research projects, collaboration with leading researchers, and significant publications solidify his reputation as a leader in his field. As a promising scientist with a bright future, Garagan’s innovative contributions make him a worthy candidate for the Best Researcher Award, and his continued research is likely to further shape the future of organic chemistry and drug development.