Dr. Marian Mitroiu is an esteemed professional in the field of biotechnology, currently affiliated with Biogen in Switzerland. With a robust background in (mention specific areas if known, e.g., neurology, immunology), Dr. Mitroiu brings extensive expertise to his role, contributing significantly to advancements in (mention specific areas of research or focus, e.g., neuroscience, rare diseases). His work is characterized by a commitment to innovation and a passion for improving healthcare outcomes through pioneering research and development efforts.
Author Profile
Scopus
Education
PhD, Biostatistics,Utrecht University, 2017 – 2022,Master of Science (MS), Epidemiology – Medical Statistics track,Utrecht University, 2017 – 2021,MSc, Biostatistics,Universitatea din București, 2014 – 2016,Master of Science (MSc), Pharmacovigilance (Drug Safety Monitoring),University of Medicine and Pharmacy “Iuliu Haţieganu”, Cluj-Napoca, 2013 – 2014,Resident Pharmacist, Clinical, Hospital, and Managed Care Pharmacy,University of Medicine and Pharmacy “Carol Davila”, Bucharest, 2013 – 2015
Experience:
cBiogen,Associate Director Biostatistics, Baar, Zug, Switzerland,December 2022 – Present (1 year 7 months),Senior Principal Biostatistician, Baar, Zug, Switzerland,August 2021 – November 2022 (1 year 4 months),College ter Beoordeling van Geneesmiddelen,Methodology Assessor, Utrecht, Netherlands,March 2018 – June 2021 (3 years 4 months),UMC Utrecht,PhD Candidate, Utrecht Area, Netherlands,January 2017 – June 2021 (4 years 6 months),European Medicines Agency,Trainee Biostatistics and Methodology, London, United Kingdom,November 2015 – October 2016 (1 year)
Skills:
- Biostatistics
- Clinical Trial Methodology
- Estimands
- ICH E9(R1) Guidelines
- Epidemiology
- Pharmacovigilance
Research Focus:
Marian Mitroiu’s research likely focuses on:,Advanced biostatistical methodologies in clinical trials,Epidemiological studies related to medical statistics,Pharmacovigilance and drug safety monitoring
Publications:
- Simoneau, G., Mitroiu, M., Debray, T.P., Pellegrini, F., Moor, C.
- Title: Visualizing the target estimand in comparative effectiveness studies with multiple treatments
- Journal: Journal of Comparative Effectiveness Research, 2024, 13(2), pp. e230089
- Leng, X., Leszczyński, P., Jeka, S., Addison, J., Zeng, X.
- Title: Comparing tocilizumab biosimilar BAT1806/BIIB800 with reference tocilizumab in patients with moderate-to-severe rheumatoid arthritis with an inadequate response to methotrexate: a phase 3, randomised, multicentre, double-blind, active-controlled clinical trial
- Journal: The Lancet Rheumatology, 2024, 6(1), pp. e40–e50
- Kersten, R.F.M.R., Öner, F.C., Arts, M.P., de Gast, A., van Gaalen, S.M.
- Title: The SNAP Trial: 2-Year Results of a Double-Blind Multicenter Randomized Controlled Trial of a Silicon Nitride Versus a PEEK Cage in Patients After Lumbar Fusion Surgery
- Journal: Global Spine Journal, 2022, 12(8), pp. 1687–1695
- Mitroiu, M., Teerenstra, S., Oude Rengerink, K., Pétavy, F., Roes, K.C.B.
- Title: Estimation of treatment effects in short-term depression studies. An evaluation based on the ICH E9(R1) estimands framework
- Journal: Pharmaceutical Statistics, 2022
- Oude Rengerink, K., Mitroiu, M., Teerenstra, S., Pétavy, F., Roes, K.C.B.
- Title: Rethinking the intention-to-treat principle: one size does not fit all
- Journal: Journal of Clinical Epidemiology, 2020, 125, pp. 198–200
- Mitroiu, M., Oude Rengerink, K., Teerenstra, S., Pétavy, F., Roes, K.C.B.
- Title: A narrative review of estimands in drug development and regulatory evaluation: Old wine in new barrels?
- Journal: Trials, 2020, 21(1), 671
- Mitroiu, M., Rengerink, K.O., Pontes, C., Van Der Lee, J.H., Roes, K.C.B.
- Title: Applicability and added value of novel methods to improve drug development in rare diseases
- Journal: Orphanet Journal of Rare Diseases, 2018, 13(1), 200
- Brakenhoff, T.B., Mitroiu, M., Keogh, R.H., Groenwold, R.H.H., van Smeden, M.
- Title: Measurement error is often neglected in medical literature: a systematic review
- Journal: Journal of Clinical Epidemiology, 2018, 98, pp. 89–97