Ayşegül Hazır | Dentistry | Research Excellence Award

Research Excellence Award

Ayşegül Hazır
Affiliation Kırıkkale University
Country Türkiye
Google Scholar -6nRwRgAAAAJ
Documents 3
Subject Area Dentistry
Event International Academic Achievements & Awards

Ayşegül Hazır
Kırıkkale University

Ayşegül Hazır is a Lecturer in the Department of Dental Prosthesis Technology at Kırıkkale University Health Services Vocational School. Her academic activities focus on prosthetic dentistry, digital dentistry, implant-supported restorations, CAD/CAM systems, and contemporary prosthodontic applications. Through teaching, research projects, scientific presentations, and scholarly publications, she contributes to the advancement of modern dental rehabilitation practices and digital transformation in dentistry.[1]

Abstract

Ayşegül Hazır is a researcher and lecturer specializing in prosthetic dentistry, digital dental technologies, implant-supported restorations, and dental materials. Her academic work focuses on integrating contemporary digital workflows into prosthodontic practice while improving clinical outcomes and educational effectiveness. Through doctoral research, scientific publications, conference presentations, and book chapters, she has contributed to advancing knowledge in CAD/CAM systems, prosthetic rehabilitation, and restorative dentistry. Her scholarly activities demonstrate a commitment to evidence-based practice, innovation in dental education, and the development of modern prosthetic treatment approaches.[1]

Keywords

Prosthetic Dentistry, Digital Dentistry, CAD/CAM Systems, Implant Prosthodontics, Dental Materials, Dental Education, Prosthesis Technology, Clinical Dentistry.

Introduction

The evolution of prosthetic dentistry increasingly relies on digital workflows, advanced biomaterials, and interdisciplinary treatment approaches. Ayşegül Hazır’s academic activities reflect these developments through research, teaching, and professional engagement focused on improving patient outcomes and educational quality in dental sciences.[3]

Research Profile

Her doctoral studies investigated the effects of various surface treatments on polyetheretherketone (PEEK) materials and their bonding performance with composite resin and resin cement systems. This work contributes to understanding the clinical applicability of advanced polymer-based restorative materials in prosthodontics.[4]

Research Contributions

  • Digital workflow applications in complete prosthesis fabrication.
  • Evaluation of CAD/CAM awareness among students.
  • Research on implant-supported prosthetic restorations.
  • Clinical assessment of contemporary prosthetic treatment approaches.

Publications

Her scholarly record includes international conference papers, book chapters, and peer-reviewed journal publications. Topics include smile design awareness, digital dentistry, CAD/CAM technologies, prosthetic rehabilitation, color concepts in dentistry, and implant-supported restoration systems.[5]

Research Impact

The impact of her work is reflected in educational innovation, dissemination of digital dentistry concepts, and contributions to prosthetic treatment methodologies. Her academic efforts support the adoption of technology-driven solutions within dental education and clinical practice.

Award Suitability

Based on her contributions to prosthetic dentistry, digital dental technologies, academic instruction, and scientific dissemination, Ayşegül Hazır demonstrates qualifications consistent with recognition in emerging dental research and academic excellence categories.

Conclusion

Ayşegül Hazır represents a contemporary academic profile combining clinical expertise, educational leadership, and research engagement. Her work contributes to the advancement of prosthodontics and digital dentistry through evidence-based investigation and knowledge dissemination.

References

  1. Kırıkkale University Academic Profile. Ayşegül Hazır, Lecturer, Department of Dental Prosthesis Technology.
  2. Hazır, A. International conference proceedings on digital dentistry and prosthetic rehabilitation.
  3. Contemporary developments in prosthetic dentistry and CAD/CAM technologies.
  4. Doctoral Thesis: Evaluation of Different Surface Treatments Applied to PEEK Polymer Surfaces.
  5. Özdoğan A., Hazır A. (2020). Analysis of Impression Methods and Techniques Used by Dentists in Complete Dentures. Selcuk Dental Journal. DOI:
    https://doi.org/10.15311/selcukdentj.563126

Yang Jilong | Medicine and Dentistry | Innovative Research Award

Innovative Research Award

Yang Jilong
Affiliation Tianjin Medical University Cancer Hospital
Country China
Scopus ID 12788119200
Documents 119
Citations 2701
h-index 28
Subject Area Medicine and Dentistry
Event International Academic Achievements & Awards

Yang Jilong
Tianjin Medical University Cancer Hospital,China

Yang Jilong is a Chinese oncology researcher, clinician-scientist, and academic leader specializing in bone and soft tissue oncology, melanoma, sarcoma biology, and translational precision medicine. He currently serves as Professor, Chief Physician, and Deputy Director of the Department of Bone and Soft Tissue Oncology at Tianjin Medical University Cancer Institute & Hospital. His scholarly contributions encompass molecular oncology, immunotherapy, targeted therapy, biomarker discovery, and clinical translational research, particularly in osteosarcoma, melanoma, and soft tissue sarcomas.[1]

Abstract

Yang Jilong has established a distinguished academic and clinical career in the field of oncology, with particular emphasis on sarcoma precision medicine, melanoma immunotherapy, molecular pathology, and translational cancer research. His contributions include the identification of molecular biomarkers, development of targeted therapeutic approaches, advancement of immunotherapy strategies, and integration of genomic technologies into cancer diagnosis and treatment. Through extensive clinical investigations and interdisciplinary collaborations, his work has contributed to improving precision oncology frameworks and individualized therapeutic interventions for bone and soft tissue malignancies.[2]

Keywords

Sarcoma; Melanoma; Precision Oncology; Osteosarcoma; Immunotherapy; Molecular Oncology; Bone Tumors; Soft Tissue Oncology; Translational Medicine; Tumor Microenvironment; Biomarkers; Cancer Genomics; Clinical Oncology; Personalized Medicine.

Introduction

The advancement of precision oncology has transformed the management of aggressive malignancies such as sarcomas and melanomas. Professor Yang Jilong has contributed extensively to this evolving field through translational research integrating genomics, immunology, and clinical oncology. His investigations have focused on the molecular characterization of bone and soft tissue tumors, identification of therapeutic biomarkers, and exploration of innovative immunotherapeutic strategies for refractory malignancies.[3]

Research Profile

Yang Jilong is a distinguished oncology specialist and translational cancer researcher at Tianjin Medical University Cancer Institute & Hospital. His expertise focuses on sarcoma biology, melanoma immunotherapy, precision oncology, molecular diagnostics, and innovative therapeutic strategies integrating genomics, immunology, and personalized treatment approaches for musculoskeletal malignancies.[5]

Research Contributions

Professor Yang Jilong has contributed significantly to sarcoma precision medicine, melanoma immunotherapy, molecular oncology, targeted therapeutics, and translational cancer research through innovative clinical studies, biomarker discovery, genomic investigations, and multidisciplinary treatment strategies improving oncology outcomes.

Publications

Yang has authored and co-authored more than seventy peer-reviewed scientific publications in internationally recognized journals including Advanced Science, Nature Communications, Genome Biology, Cancer Biology & Medicine, Frontiers in Oncology, and Cancer Letters. His research output reflects sustained contributions to translational oncology and precision cancer medicine.[2]

  • Genome-Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma. Advanced Science, 2026.
  • A single-cell analysis reveals tumor heterogeneity and immune environment of acral melanoma. Nature Communications, 2022.
  • IGFBP2 regulates PD-L1 expression by activating the EGFR-STAT3 signaling pathway in malignant melanoma. Cancer Letters, 2020.
  • Mesenchymal to epithelial transition in sarcomas. European Journal of Cancer, 2014.
  • Genetic amplification of VEGFA pathway genes in osteosarcoma. Cancer, 2011.

Research Impact

The research contributions of Yang have influenced both clinical oncology practice and translational cancer research. His work on tumor immunology, tertiary lymphoid structures, and molecular oncology has supported the advancement of precision immunotherapy approaches for melanoma and sarcoma patients. Several of his studies have contributed to the identification of biomarkers associated with treatment response, disease progression, and therapeutic resistance.[3]

Award Suitability

Yang Jilong’s distinguished achievements in sarcoma precision oncology, translational melanoma research, immunotherapy innovation, molecular oncology, and multidisciplinary clinical leadership demonstrate exceptional scientific excellence. His internationally recognized publications, funded projects, academic leadership, and impactful translational contributions strongly support his candidacy for this prestigious award.

Concluion

Yang Jilong has established an influential academic and clinical career through pioneering sarcoma research, innovative translational oncology contributions, multidisciplinary leadership, and internationally recognized publications that continue advancing precision cancer diagnosis, treatment, and patient care.

References

  1. Tianjin Medical University Cancer Institute & Hospital. (2026). Professional profile of Professor Yang Jilong.
  2. Wang Z, Liu H, Wang X, et al. (2026). Genome-Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma. Advanced Science.
    https://doi.org/10.1002/advs.202515158
  3. Zhang C, Shen H, Yang T, et al. (2022). A single-cell analysis reveals tumor heterogeneity and immune environment of acral melanoma. Nature Communications.
    https://www.nature.com/articles/s41467-022-34937-1
  4. Li T, Zhang C, Zhao G, et al. (2020). IGFBP2 regulates PD-L1 expression by activating the EGFR-STAT3 signaling pathway in malignant melanoma. Cancer Letters.
    https://doi.org/10.1016/j.canlet.2020.01.015
  5. Yang J, Yang D, Sun Y, et al. (2011). Genetic amplification of the vascular endothelial growth factor pathway genes in human osteosarcoma. Cancer.
    https://doi.org/10.1002/cncr.26121

Qian Li | Dentistry | Innovative Research Award

Innovative Research Award

Qian Li
Peking University School and Hospital of Stomatology, China
Qian Li
Affiliation Peking University School and Hospital of Stomatology
Country China
Scopus ID 57287787300
Documents 32
Citations 1369
h-index 19
Subject Area Dentistry
Event International Academic Achievements & Awards

Qian Li is an Associate Professor in the Department of Orthodontics at Peking University School and Hospital of Stomatology. Her academic work integrates molecular biology, epigenetics, stem cell regulation, and skeletal biology, with emphasis on understanding the epigenetic regulation of mesenchymal stem cell function in bone metabolism-associated diseases. Her research activities combine translational biomedical science with orthodontic and regenerative medicine applications, contributing to the understanding of cellular mechanisms involved in skeletal homeostasis and tissue remodeling.[1]

Abstract

Qian Li’s scholarly work focuses on epigenetic mechanisms governing stem cell differentiation, skeletal maintenance, bone metabolism, and orthodontic biology. Her research portfolio spans molecular signaling pathways, chromatin remodeling, cellular senescence, and stem cell responses to mechanical stimulation. Through interdisciplinary biomedical investigation, her work contributes to advancing understanding of disease-associated bone metabolism alterations and regenerative therapeutic strategies.[2]

Keywords

Orthodontics; Epigenetics; Mesenchymal Stem Cells; Bone Metabolism; Skeletal Homeostasis; Molecular Biology; Chromatin Remodeling; Osteogenic Differentiation; Dental Stem Cells; Regenerative Medicine

Introduction

Advances in molecular biology and stem cell science have significantly transformed understanding of skeletal biology and oral health sciences. Epigenetic regulation represents an important frontier in identifying mechanisms underlying tissue regeneration and disease progression. Qian Li has developed an academic profile positioned at the intersection of orthodontics, molecular epigenetics, and regenerative medicine, contributing research focused on mechanobiology and cellular regulation in bone-associated diseases.[3]

Research Profile

  • Associate Professor, Department of Orthodontics, Peking University School and Hospital of Stomatology
  • Ph.D. in Biochemistry and Molecular Biology, Peking University Health Science Center (2008–2012)
  • Bachelor of Medicine, Basic Medical Sciences, Peking University Health Science Center (2003–2008)
  • Postdoctoral training at Peking University Health Science Center (2012–2014)
  • Research specialization in epigenetic regulation of mesenchymal stem cells and skeletal biology

Research Contributions

Qian Li has contributed to research investigating epigenetic regulation mechanisms controlling skeletal homeostasis, osteogenic differentiation, chromatin dynamics, and mechanobiological responses. Published studies include investigations into SUV39H1-dependent methylation pathways, SOX9 stability regulation in dental pulp stem cells, FOXQ1-SIRT4-GDH signaling networks, and EZH2-associated mechanotransduction pathways in periodontal ligament stem cells.[4]

Her work further explores molecular pathways relevant to ferroptosis regulation, cellular senescence, and orthodontic mechanical response biology, supporting translational advances within oral and skeletal biomedical sciences.

Publications

  1. SUV39H1-dependent methyl-degron is a critical regulator of skeletal homeostasis. Cell Reports. 2025.
  2. Lysine 68 Methylation-Dependent SOX9 Stability Control Modulates Chondrogenic Differentiation in Dental Pulp Stem Cells. Advanced Science. 2023.
  3. Epigenetic activation of secretory phenotypes in senescence by the FOXQ1-SIRT4-GDH signaling pathway. Cell Death & Disease. 2023.
  4. CRL4(DCAF8)-dependent regulation over chromatin remodeler LSH orchestrates epigenetic dynamics in ferroptosis. Cell Death & Differentiation. 2021.
  5. EZH2 reduction maintains super-enhancer polarization against compressive stress in periodontal ligament stem cells. Cell Death & Disease. 2020.

Research Impact

Research outputs authored and co-authored by Qian Li span internationally recognized biomedical journals and address mechanistic biological questions with implications for bone metabolism, orthodontics, tissue engineering, and regenerative medicine. Her funded research programs include competitive grants from the National Natural Science Foundation of China and Beijing Natural Science Foundation, reflecting sustained scholarly activity and scientific leadership.

Award Suitability

The academic profile demonstrates alignment with recognition frameworks emphasizing sustained scholarly productivity, externally funded research, translational biomedical contributions, interdisciplinary scientific advancement, and peer-reviewed publication achievements. Research leadership in stem cell biology and epigenetic regulation supports consideration within academic excellence recognition initiatives.

Conclusion

Qian Li’s research trajectory reflects sustained contributions to molecular biology and orthodontic science through investigations addressing epigenetic mechanisms, stem cell function, and skeletal biology. Her academic activities integrate foundational biological discovery with clinical and translational relevance, supporting continuing advancement within dental and biomedical sciences.

References

  1. Peking University School and Hospital of Stomatology. Faculty academic information and institutional profile.
  2. Li Q. Research profile and epigenetic regulation investigations in skeletal biology and stem cell science.
  3. Li Q et al. Cellular and molecular mechanisms in orthodontic biology and epigenetic regulation.
  4. Li Q et al. Cell Reports. 2025. DOI:https://doi.org/10.1016/j.celrep.2025.115910